Meta-analysis on 39 randomised control trials for 15 different conditions (5777 patients)
Following a medical procedure: Out 24 RCTs-No outcomes improved significantly
8 worsened significantly in some procedures Lumbar puncture – vertigo, nausea and vomiting (no significant improvement in headache) Spinal anaesthesia – headache, back pain Radiculography – headache, nausea,vomiting, dizziness Cardiac catheterisation – haematoma,pain, bleeding
As a treatment Out of 19 RCTs-No outcomes improved significantly
9 worsened significantly for some conditions Acute low back pain – disability (day 1, day 7 and day 28), normal activity, pain Labour – length of stay, contraction frequency, assisted delivery, anaglesia required, APGAR score Proteiunuric hypertension during pregnancy – plasma urea and urate, premonitory symptoms of eclampsia Myocardial infarction – VTE, mortality, non-fatal reinfarction, ischaemia or congestive cardiac failure Acute infection hepatitis – time to recovery A. There is no evidence that bed rest has any significant beneficial effect when used as a treatment or following a procedure. In some disorders, it seems to be harmful.